Thalassaemia Test
Last updated: 29 Oct 2024.
Blood tests and genetic screenings are the primary tools used to diagnose thalassaemia. Thalassaemia is a genetic
blood disorder that affects the body's ability to produce
haemoglobin, the protein in red blood cells that carries oxygen. This condition
can lead to anaemia, fatigue, growth delays in children, and other health complications.
It is estimated that about 3% of the population in Singapore carries the thalassaemia gene.
Thalassaemia testing is vital for the early detection of the disorder,
enabling informed family planning by identifying carriers and affected
individuals.
Thalassaemia Types
There are two types of thalassaemia: alpha thalassaemia and beta thalassaemia, which affect the alpha globin and beta globin protein chains, respectively. Each person has four alpha globin genes – two inherited from each parent – and two beta globin genes – one inherited from each parent. Thalassaemia can also be classified as minor, where the individual is a carrier of the thalassaemia gene but does not have the disease, or major, where the individual has developed the disease and requires treatment.
Thalassaemia Symptoms
Thalassaemia symptoms vary based on whether the individual has minor or major thalassaemia, and the type (alpha or beta). General symptoms include:
- Anaemia - fatigue, breathlessness, pale skin, jaundice
- Enlarged spleen and liver
- Bone issues such as osteoporosis
In children with thalassaemia, additional symptoms can include:
- Stunted growth and delayed physical development
- Delayed puberty
- Bone deformities
- Frequent infections due to enlarged spleen
Children born with thalassaemia major usually experience severe anaemia throughout their lives, requiring regular blood transfusions. A bone marrow transplant may be considered a potential cure. In severe cases, particularly in alpha thalassaemia where all four alpha globin genes are affected, the condition can be fatal.
Testing for Thalassaemia
Blood Tests
Testing for thalassaemia typically involves a full blood count to measure haemoglobin levels and identify abnormalities in red blood cells. Haemoglobin electrophoresis, a test that separates the different types of haemoglobin in the blood, is also used to determine the presence and type of thalassaemia. Prenatal screenings commonly test if a parent is a carrier of the thalassaemia gene or has the condition.
Genetic Screening
Genetic screening involves analysing DNA to identify mutations associated with thalassaemia. This test can determine if an individual is a carrier or if they have the disease. Genetic screening is particularly useful for couples planning to have children, as it helps assess the risk of passing the disorder to offspring.
Thalassaemia Test Cost in Singapore
At ATA Medical, we offer full blood count tests and haemoglobin electrophoresis with the following prices:
| Test | Price* |
|---|---|
| Consultation | From $38.15 |
| Full Blood Count | $17.44 |
| Full Blood Count (with Erythrocyte Sedimentation Rate [ESR]) | $26.16 |
| Haemoglobin (Hb) Electrophoresis | $59.95 |
| ANM6 Thalassaemia Profile Screen (Full Blood Count, Peripheral Blood Film, Haemoglobin (Hb) Electrophoresis) | $74.12 |
| ANM7 Thalassaemia Profile Screen (Full Blood Count, Peripheral Blood Film, Haemoglobin (Hb) Electrophoresis, Folic Acid, Vitamin B12, Ferritin) | $103.55 |
For a more comprehensive overview of your health, you can consider our health screening packages which includes full blood count testing.
Where to Test for Thalassaemia in Singapore
You can consult our doctors and get tested for thalassaemia at any of our two convenient located clinics:
- Tanjong Pagar Medical Clinic (Closest MRT: Tanjong Pagar EW15)
- Orchard Clinic (Closest MRT: Orchard Boulevard TE13)
Summary
Testing for thalassaemia can determine if you have the condition or if it's causing underlying health issues, enabling early management to improve health outcomes. More importantly, knowing if you are a carrier of the thalassaemia gene can guide family planning, given the potential impact of the condition on future children. If you are experiencing anaemic symptoms or are concerned if you are a carrier, schedule an appointment today with our doctors to discuss testing options.
How Do I Book a Thalassaemia Test Appointment?
ATA Medical @ Orchard
Nearest MRT: Orchard Boulevard Station (TE13)
Contact Number: 6322 7331
Email: camden@atamed.sg
Opening Hours:
Mon - Fri: 8:30 AM to 12:30 PM, 1:30 PM to 5:30 PM
Sat: 8:30 AM to 12:30 PM
Sun & PH: Closed
ATA Medical @ Tanjong Pagar
Nearest MRT: Tanjong Pagar Station (EW15)
Contact Number: 6223 0682
Email: hi@atamed.sg
Opening Hours:
Mon - Fri: 8:30 AM to 12:30 PM, 1:30 PM to 5:30 PM
Sat: 8:30 AM to 12:30 PM
Sun & PH: Closed