Urea Breath Test

Helicobacter pylori, also known as H. pylori, is a bacterium found in the stomach lining, implicated in several gastrointestinal conditions, including gastritis, ulcers, and potentially leading to gastric cancer. The significance of these conditions necessitates early and precise detection of H. pylori. Among the various methods available for screening H. pylori, the Urea Breath Test (UBT) is noted for its non-invasive approach and efficiency.

The Urea Breath Test is a diagnostic tool used to detect the presence of H. pylori. This method exploits the bacterium's unique ability to convert urea—a chemical compound that is naturally present in the human body—into carbon dioxide. This capability forms the basis of the UBT, which is a key method in diagnosing H. pylori-induced conditions.

• Non-invasive Procedure: The UBT is a more patient-friendly option compared to invasive procedures like endoscopies, offering a more comfortable experience for individuals undergoing testing.
• Accuracy: With high sensitivity and specificity, the UBT is effective in identifying H. pylori infections, ensuring reliable detection.
• Speed of Results: The UBT is advantageous for its quick turnaround time in producing results, which aids in the prompt initiation of treatment plans.
• Safety: Especially when using the Carbon-13 (C13) isotope, the UBT involves minimal radiation, making it suitable for a wide range of patients, including pregnant women and children.

While the Urea Breath Test is useful in detecting H. pylori, certain factors may influence its accuracy:

• Recent Antibiotics or Proton Pump Inhibitors: These medications can temporarily decrease the levels of H. pylori in the stomach, which may result in false-negative outcomes.
• Past Stomach Surgery: Previous surgeries on the stomach may alter the distribution and activity of H. pylori, affecting the accuracy of the test.

Despite these potential limitations, the Urea Breath Test remains a valuable tool for the detection of H. pylori. It plays an essential role in the early diagnosis and management of H. pylori-related conditions, contributing to the prevention of more severe gastrointestinal issues.

Patients should do the following:

• Fast for at least 3-6 hours prior to the test.
• Stop smoking for at least 30 minutes before the test.
• Stop taking antibiotics for at least 4 weeks prior to the test, especially Amoxicillin (Amoxil, Moxam), Bismuth tricitrate (Denol), Clarithromycin (Klacid), Fasigyn (Tinidazole), Metronidazole (Flagyl), and Tetracycline (Tetrex, Mysteclin, Achromycin).
• Stop taking proton pump inhibitors in the form of Losec (Omeprazole), Somac (Pantoprazole Sodium Sesquihydrate), Zoton (Lansoprazole), and Nexium for at least 1 week before the test.

Testing positive for Helicobacter pylori (H. pylori) via the Urea Breath Test (UBT) indicates the presence of the bacterium in the stomach lining, which may contribute to various gastrointestinal conditions. It’s important to discuss the results with a doctor to understand the implications fully and to determine the most appropriate treatment plan.

Treatment Options

• Antibiotic Therapy: A common approach involves a combination of antibiotics to eradicate the H. pylori infection. The specific antibiotics and the duration of treatment may vary, based on individual factors and resistance patterns.
• Acid Suppression Therapy: Proton pump inhibitors or other acid-suppressing medications may be prescribed alongside antibiotics to help reduce stomach acid, aiding in the healing process and increasing the efficacy of antibiotics.
• Follow-Up Testing: After completing the treatment, follow-up testing is often recommended to ensure the infection has been successfully eradicated. This may include a repeat UBT or other diagnostic tests, as advised by a healthcare professional.

Health Screening at ATA Medical is affordable and easy. You can do your Helicobacter pylori screen test at 2 convenient locations across Singapore.

• Tanjong Pagar Medical Clinic (Closest MRT: Tanjong Pagar EW15)
• Orchard Clinic (Closest MRT: Orchard Boulevard TE13)

You may also want to explore our comprehensive health screening packages. Our Royal package ($612), Jewel package ($1299), and Marvel package ($2100) each have bundled ECG tests.